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Volume 33 , Issue 4
July/August 2013
Pages e101–e110

Long-Term Bony Integration and Resorption Kinetics of a Xenogeneic Bone Substitute After Sinus Floor Augmentation: Histomorphometric Analyses of Human Biopsy Specimens

Marcus O. Klein, MD, DMD, PhD/Peer W. Kämmerer, MD, DMD/Hermann Götz, PhD/Heinz Duschner, PhD/Wilfried Wagner, MD, DMD, PhD

PMID: 23820714
DOI: 10.11607/prd.1469

In this case series, a systematic histomorphometric analysis of two human bone biopsy specimens was conducted 1 and 5 years after grafting with a xenogeneic bovine bone substitute material (BSM). While the 1-year specimen still showed extensive signs of an active desmal ossification, the specimen after 5 years mainly showed mature lamellar bone without bone turnover or remodeling. A completed bony integration without extensive resorption of the BSM particles could be detected. Altogether, a good integration in the bone with osteoconduction and a high biocompatibility was seen. (Int J Periodontics Restorative Dent 2013;33:e101–e110. doi: 10.11607/prd.1469)

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